Sennidin B, CAS 517-44-2

Product Description: Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation [1][2].

Applications: Metabolism-sugar/lipid metabolism

Formula: C30H18O10

References: [1]Furuta A, et al. Identification of Hydroxyanthraquinones as Novel Inhibitors of Hepatitis C Virus NS3 Helicase. Int J Mol Sci. 2015 Aug 7;16(8):18439-53./[2]Daigo Abe, et al. Sennidin stimulates glucose incorporation in rat adipocytes. Life Sciences. 2006.

CAS Number: 517-44-2

Molecular Weight: 538.46

Compound Purity: 98.83

Research Area: Infection; Metabolic Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Akt;GLUT;HCV

• Artikelnummer: MEXHY-N6935-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N6935-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK