Product Description: Silybin B (Silibinin B), a flavonolignan separated from Silybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease agent candidate[1][2].
Applications: Cancer-programmed cell death
Formula: C25H22O10
References: [1]An-Shen Lin, et al. Cancer Preventive Agents. 7. Antitumor-Promoting Effects of Seven Active Flavonolignans from Milk Thistle (Silybum marianum.) on Epstein-Barr Virus Activation, Pharmaceutical Biology, 45:10, 735-738./[2]Sciacca MFM, et al. Inhibition of Aβ Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry. ACS Chem Neurosci. 2017 Aug 16;8(8):1767-1778.
CAS Number: 142797-34-0
Molecular Weight: 482.44
Compound Purity: 99.90
Research Area: Cancer; Neurological Disease
Solubility: DMSO : 250 mg/mL (ultrasonic)
Target: Amyloid-β