Product Description: Sodium new houttuyfonate (SNH) is a partially reversible NDM-1 inhibitor with an IC50 of 14.2 μM. Sodium new houttuyfonate is an inhibitor against renin and angiotensin I converting enzyme (ACE). Sodium new houttuyfonate can recover the antibacterial activity of Meropenem (HY-13678) against E. coli BL21/pET15b-blaNDM-1[1].
Applications: COVID-19-immunoregulation
Formula: C14H27NaO5S
References: [1]Lifang Wang, et al. Novel partially reversible NDM-1 inhibitors based on the naturally occurring houttuynin. Bioorg Chem. 2024 Apr 3:147:107328.