Product Description: Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2].
Applications: COVID-19-immunoregulation
Formula: C15H10O5
References: [1]Mi-Young Song, et al. Sulfuretin attenuates allergic airway inflammation in mice. Biochem Biophys Res Commun. 2010 Sep 10;400(1):83-8./[2]Chen, H., et al. Isolation of sulfuretin and butin from Rhus verniciflua Stokes using medium-pressure liquid chromatography and their tyrosinase inhibitory effects. BioRes. 11(1), 759-771.
CAS Number: 120-05-8
Molecular Weight: 270.24
Compound Purity: 98.91
Research Area: Inflammation/Immunology
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: NF-κB