Tetramethylcurcumin, CAS 52328-97-9

Product Description: Tetramethylcurcumin (FLLL31), derived from curcumin, specifically suppresses the phosphorylation of STAT3 by binding selectively to Janus kinase 2 and the STAT3 Src homology-2 domain. Tetramethylcurcumin exhibits anti-inflammatory and anti-cancer effects[1][2].

Applications: COVID-19-immunoregulation

Formula: C25H28O6

References: [1]Lin L, et al. Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells. Cancer Res. 2010 Mar 15;70(6):2445-54./[2]Yuan S, et al. FLLL31, a derivative of curcumin, attenuates airway inflammation in a multi-allergen challenged mouse model. Int Immunopharmacol. 2014 Jul;21(1):128-36.

CAS Number: 52328-97-9

Molecular Weight: 424.49

Compound Purity: 99.91

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Apoptosis;STAT

• Artikelnummer: MEXHY-N2521-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N2521-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK