Product Description: Trichodermamide B is a JAK/STAT3 inhibitor. Trichodermamide B exhibits a potent antiproliferative activity with an IC50 value of 0.12 μM against HCT116. Trichodermamide B induces cell apoptosis and has anti-cancer effects[1].
Formula: C20H19ClN2O8
References: [1]Yue Zhou, et al. Structural Optimization of Marine Natural Product Pretrichodermamide B for the Treatment of Colon Cancer by Targeting the JAK/STAT3 Signaling Pathway. J Med Chem. 2024 Jun 18.