Uridine 5'-diphosphate (sodium salt), CAS 21931-53-3

Product Description: Uridine 5'-diphosphate sodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52) and a potent P2Y14 antagonist (pEC50=7.28). Uridine 5'-diphosphate sodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C9H14N2O12P2.xNa

References: [1]Jacobson KA, et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal. 2009 Mar;5(1):75-89./[2]Kim B, et al. Uridine 5'-diphosphate induces chemokine expression in microglia and astrocytes through activation of the P2Y6 receptor. J Immunol. 2011 Mar 15;186(6):3701-9.

CAS Number: 21931-53-3

Molecular Weight: N/A

Research Area: Metabolic Disease; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: DNA/RNA Synthesis;Endogenous Metabolite;P2Y Receptor

• Artikelnummer: MEXHY-W010820-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W010820-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK