Verticillin A, CAS 889640-30-6

Product Description: Verticillin A is a selective HMTase inhibitor. Verticillin A inhibits SUV39H1, SUV39H2, G9a, HTM, MLL1 and GLP. Verticillin A is a MEK inhibitor. Verticillin A induces DNA damage and apoptosis. Verticillin A has anticancer effects against various cancers. Verticillin A is also an antibiotic[1][2][3].

Formula: C30H28N6O6S4

References: [1]Salvi A, et al. Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage. Mol Cancer Ther. 2020 Jan;19(1):89-100./[2]Schenke D, et al. Verticillin A is likely not produced by Verticillium sp. J Antibiot (Tokyo). 2011 Jul;64(7):523-4. /[3]Guan Y, et al. Verticillin A increases the BIMEL/MCL-1 ratio to overcome ABT-737-resistance in human colon cancer cells by targeting the MEK/ERK pathway. Biochem Biophys Res Commun. 2021 Aug 27;567:22-28.

CAS Number: 889640-30-6

Molecular Weight: 696.84

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Antibiotic;Apoptosis;Histone Methyltransferase;MEK

• Artikelnummer: MEXHY-126805-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-126805-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK