4-Thiouridine 5′-triphosphate (tetralithium), CAS 20188-72-1

Product Description: 4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetralithium is a potent P2Y2 and P2Y4 receptor agonist, with EC50s of 35 and 350 nM for hP2Y2 and hP2Y4, respectively. 4-Thiouridine 5′-triphosphate tetralithium can be used in the study of crosslinking experiments, labeling of transcriptional complex[1][2].

Applications: COVID-19-immunoregulation

Formula: C9H11Li4N2O14P3S

References: [1]Jacobson KA, et, al. Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors. Biochem Pharmacol. 2006 Feb 14;71(4):540-9./[2]Bartholomew B, et, al. RNA contacts subunits IIo and IIc in HeLa RNA polymerase II transcription complexes. J Biol Chem. 1986 Oct 25;261(30):14226-31.

CAS Number: 20188-72-1

Molecular Weight: 523.94

Compound Purity: 85.0

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: P2Y Receptor

• Artikelnummer: MEXHY-154840-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-154840-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK