α-CGRP (mouse, rat), CAS 83651-90-5

Product Description: α-CGRP (mouse, rat), a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies[1][2][3][4].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C162H262N50O52S2

References: [1]Whitby K, et al. Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo. J Virol. 2005 Jul;79(14):8698-706./[2]Xu H, et al. Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses. Immunity. 2019 Oct 15;51(4):696-708.e9./[3]Arulmani U, et al. Effects of the calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS on alpha-CGRP-induced regional haemodynamic changes in anaesthetised rats. Basic Clin Pharmacol Toxicol. 2004 Jun;94(6):291-7./[4]Park SH, et al. Role of α-CGRP in the regulation of neurotoxic responses induced by kainic acid in mice. Peptides. 2013 Jun;44:158-62.

CAS Number: 83651-90-5

Molecular Weight: 3806.25

Compound Purity: 99.39

Research Area: Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Solubility: H2O : ≥ 100 mg/mL

Target: CGRP Receptor

• Artikelnummer: MEXHY-P0203-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P0203-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK