α-Conotoxin Vc1.1 (TFA)

Product Description: α-Conotoxin Vc1.1 TFA is a disulfide-bonded peptide isolated from Conus victoriae and is a selective nAChR antagonist. α-Conotoxin Vc1.1 TFA inhibits α3α5β2, α3β2 and α3β4 with IC50s of 7.2 μM, 7.3 μM and 4.2 μM, respectively, and has less inhibitory effect on other nAChR subtypes. α-Conotoxin Vc1.1 TFA has the potential for neuropathic pain reserach[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C73H104F3N23O27S4

References: [1]Richard J Clark, et al. The Synthesis, Structural Characterization, and Receptor Specificity of the Alpha-Conotoxin Vc1.1. J Biol Chem. 2006 Aug 11;281(32):23254-63./[2]Narmatha Satkunanathan, et al. Alpha-conotoxin Vc1.1 Alleviates Neuropathic Pain and Accelerates Functional Recovery of Injured Neurones. Brain Res. 2005 Oct 19;1059(2):149-58.

Molecular Weight: 1921.00

Compound Purity: 97.57

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: nAChR

• Artikelnummer: MEXHY-125777A-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-125777A-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK