Abaloparatide, CAS 247062-33-5

Product Description: Abaloparatide (BA 058) is a parathyroid hormone receptor 1 (PTHR1) analog. Abaloparatide also is a selective PTHR1 activator. Abaloparatide enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide enhances bone formation and cortical structure in mice. Abaloparatide has the potential for the research of osteoporosis[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C174H300N56O49

References: [1]Sahbani K, et al. Abaloparatide exhibits greater osteoanabolic response and higher cAMP stimulation and β-arrestin recruitment than teriparatide. Physiol Rep. 2019 Oct;7(19):e14225./[2]Varela A, et al. One Year of Abaloparatide, a Selective Activator of the PTH1 Receptor, Increased Bone Formation and Bone Mass in Osteopenic Ovariectomized Rats Without Increasing Bone Resorption. J Bone Miner Res. 2017 Jan;32(1):24-33.

CAS Number: 247062-33-5

Molecular Weight: 3960.59

Compound Purity: 99.94

Research Area: Metabolic Disease

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Arrestin;Thyroid Hormone Receptor

• Artikelnummer: MEXHY-108742-50
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-108742-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK