AFG210, CAS 228400-22-4

Product Description: AFG210 is a potent multi-target kinase inhibitor that primarily inhibits Abl kinase (IC50=330 nM), and also has inhibitory effects on other kinases such as B-Raf, C-Raf, FGFR-1, RET and VEGF receptors. AFG210 can be used to study chronic myeloid leukemia and other diseases with abnormal activation of Abl kinase[1].

Formula: C19H14F3N3O2

References: [1]AC Backes, et al. Small-molecule inhibitors binding to protein kinase. Part II: the novel pharmacophore approach of type II and type III inhibition. Expert opinion on drug discovery, 3(12), 1427-1449.

CAS Number: 228400-22-4

Molecular Weight: 373.33

Research Area: Cancer

Target: Bcr-Abl;FGFR;Raf;RET;VEGFR

• Artikelnummer: MEXHY-18817-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-18817-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK