AKE-72, CAS 2566525-18-4

Product Description: AKE-72 (compound 5) is a potent inhibitor of Pan-BCR-ABL. AKE-72 inhibits BCR-ABLWT, BCR-ABLT315, BCR-ABLE255K, BCR-ABLF3171, BCR-ABLH396P and BCR-ABLQ252H with IC50s of [1].

Applications: Cancer-Kinase/protease

Formula: C30H29F3N6O

References: [1]3-((3-amino-1H-indazol-4-yl)ethynyl)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide (AKE-72), a potent Pan-BCR-ABL inhibitor including the T315I gatekeeper resistant mutant. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2228515.

CAS Number: 2566525-18-4

Molecular Weight: 546.59

Compound Purity: 98.29

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Bcr-Abl

• Artikelnummer: MEXHY-157327-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-157327-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK