Product Description: anti-TNBC agent-7 (Compound 13c) possesses anticancer activity, serving as a molecular probe to recognize and regulate the signal transduction of the USP21/JAK2/STAT3 axis, exhibiting nanomolar-level cytotoxicity against MDA-MB-231 and HCC-1806 cancer cells, effectively combating triple-negative breast cancer (TNBC)[1].
Applications: Cancer-Kinase/protease
Formula: C26H24F3N3O4
References: [1]Long L, et al. Discovery of novel small molecules targeting the USP21/JAK2/STAT3 axis for the treatment of triple-negative breast cancer. Eur J Med Chem. Published online May 16, 2024.
Molecular Weight: 499.48
Research Area: Cancer
Target: JAK;STAT