Product Description: ARF(26–44), cell-permeable is a cell-penetrating peptide derived from a specific amino acid sequence of the p14ARF tumor suppressor protein. As a functional inhibitor of FoxM1, ARF(26–44) cell-permeable shows significant anti-tumor activity in the treatment of mouse hepatocellular carcinoma (HCC), significantly increasing tumor cell apoptosis and reducing tumor cell proliferation and angiogenesis. ARF(26–44), cell-permeable can be used in research on tumor therapy[1].
Formula: C149H267N69O33S
References: [1]Gusarova G A, et al. A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment[J]. The Journal of clinical investigation, 2007, 117(1): 99-111.
CAS Number: 935732-44-8
Molecular Weight: 3585.22
Research Area: Cancer
Target: Apoptosis