Product Description: AZ14133346 (compound 36) is a potent and selective inhibitor of EGFR Exon20 insertions, with the IC50 of 85 nM. AZ14133346 plays an important role in cancer research[1].
Formula: C29H27N5O2
References: [1]Clare Thomson, et al. Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations. J Med Chem. 2024 Jun 13;67(11):8988-9027.