English
AZ683, CAS 953798-95-3
AZ683, CAS 953798-95-3
Artikelnummer
MEXHY-159108-0
Verpackungseinheit
Get quote
Hersteller
MedChemExpress
Verfügbarkeit:
wird geladen...
Preis wird geladen...
Product Description: AZ683 is a potent and selective 3-amido-4-anilinoquinoline CSF1R inhibitor. AZ683 has high affinity for CSF1R (Ki=8 nM; IC50=6 nM). AZ683 has good oral bioavailability. [11C]AZ683 can be used as a positron emission tomography (PET) radiotracer for colony stimulating factor 1 receptor (CSF1R)[1][2].
Formula: C23H25F2N5O2
References: [1]Tanzey SS, et al. Synthesis and Initial In Vivo Evaluation of [11C]AZ683-A Novel PET Radiotracer for Colony Stimulating Factor 1 Receptor (CSF1R). Pharmaceuticals (Basel). 2018 Dec 13;11(4):136. /[2]Scott DA, et al. Mitigation of cardiovascular toxicity in a series of CSF-1R inhibitors, and the identification of AZD7507. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4591-6.
CAS Number: 953798-95-3
Molecular Weight: 441.47
Research Area: Cardiovascular Disease
Target: c-Fms
Formula: C23H25F2N5O2
References: [1]Tanzey SS, et al. Synthesis and Initial In Vivo Evaluation of [11C]AZ683-A Novel PET Radiotracer for Colony Stimulating Factor 1 Receptor (CSF1R). Pharmaceuticals (Basel). 2018 Dec 13;11(4):136. /[2]Scott DA, et al. Mitigation of cardiovascular toxicity in a series of CSF-1R inhibitors, and the identification of AZD7507. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4591-6.
CAS Number: 953798-95-3
Molecular Weight: 441.47
Research Area: Cardiovascular Disease
Target: c-Fms
| Artikelnummer | MEXHY-159108-0 |
|---|---|
| Hersteller | MedChemExpress |
| Hersteller Artikelnummer | HY-159108-0 |
| Verpackungseinheit | Get quote |
| Mengeneinheit | STK |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
Verwandte Artikel
Markieren Sie die Artikel, um Sie dem Warenkorb hinzuzufügen oder
Immer für Sie da
Dr. Andreas Bergmann
