Baricitinib (Standard), CAS 1187594-09-7

Product Description: Baricitinib (Standard) is the analytical standard of Baricitinib. This product is intended for research and analytical applications. Baricitinib (LY3009104; INCB028050) is a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC50s of 5.9 nM and 5.7 nM, respectively.

Formula: C16H17N7O2S

References: [1]Fridman JS, et al. Selective inhibition of JAK1 and JAK2 is efficacious in rodent models of arthritis: preclinical characterization of INCB028050. J Immunol. 2010 May 1;184(9):5298-307./[2]Jabbari A, et al. Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib. EBioMedicine. 2015 Feb 26;2(4):351-5./[3]Khan IM, et al. Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration resistance. Int J Obes (Lond). 2015 Nov;39(11):1607-18.

CAS Number: 1187594-09-7

Molecular Weight: 371.42

Research Area: Inflammation/Immunology

Target: JAK

• Artikelnummer: MEXHY-15315R-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15315R-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK