Product Description: Berninamycin A is a cyclic thiopeptide antibiotic first isolated from S. bernensis. It inhibits protein biosynthesis in Gram positive bacteria through binding with ribosomal subunits. Cyclic thiopeptide antibiotics, including berninamycin A, induce the transcriptional activator TipA in Streptomyces.
Applications: COVID-19-immunoregulation
Formula: C51H51N15O15S
References: [1]Chiu, et al. Broad spectrum thiopeptide recognition specificity of the Streptomyces lividans TipAL protein and its role in regulating gene expression. J. Biol. Chem. 274(29), 20578-20586 (1999).
CAS Number: 58798-97-3
Molecular Weight: 1146.11
Research Area: Infection
Target: Bacterial