BIIB129, CAS 2770960-52-4

Product Description: BIIB129 is a covalent, selective, small molecule inhibitor of Bruton's tyrosine kinase (BTK) capable of penetrating the blood-brain barrier. BIIB129 inhibits the activity of BTK by covalently binding to Cys481 in BTK, thereby affecting the function of B cells and myeloid cells. BIIB129 can be used in multiple sclerosis (MS) research[1].

Applications: Neuroscience-Neuromodulation

Formula: C19H22N6O2

References: [1]Himmelbauer M K, et al. Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis[J]. Journal of Medicinal Chemistry, 2024.

CAS Number: 2770960-52-4

Molecular Weight: 366.42

Research Area: Neurological Disease

Target: Btk

• Artikelnummer: MEXHY-163565-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-163565-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK