BL-1020 (mesylate), CAS 916898-61-8

Product Description: BL-1020 mesylate is the mesylate salt form of BL-1020. BL-1020 mesylate is an antipsychotic agent. BL-1020 mesylate is inhibitor for dopamine receptor and serotonin receptor (5-HT receptor), with Ki of 0.066, 0.062 and 0.21 nM, for D2L, D2S and 5-HT2A receptors, respectively. BL-1020 mesylate is agonist for GABAA receptor with Ki of 3.74 μM, and enhances the GABA release. BL-1020 mesylate exhibits high affinity with histamine receptor (Ki is 0.47 nM). BL-1020 mesylate reduces Amphetamine-induced hyperactivity, with lower catalepsy and sedation. BL-1020 mesylate is blood-brain barrier penetrate[1].

Applications: Neuroscience-Neuromodulation

Formula: C26H37ClN4O5S2

References: [1]Geffen Y, et al., BL-1020: a novel antipsychotic drug with GABAergic activity and low catalepsy, is efficacious in a rat model of schizophrenia. Eur Neuropsychopharmacol. 2009 Jan;19(1):1-13.

CAS Number: 916898-61-8

Molecular Weight: 585.18

Research Area: Neurological Disease

Target: 5-HT Receptor;Dopamine Receptor;GABA Receptor;Histamine Receptor

• Artikelnummer: MEXHY-111136-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-111136-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK