c-Met degrader-1

Product Description: c-Met degrader-1 (Compound H11) is an orally active c-Met degrader (through the ubiquitin proteasome system). c-Met degrader-1 has anti-hepatocellular carcinoma activity (HCC) and inhibits tumor growth in MHCC97H xenografts. c-Met degrader-1 inhibits HCC cell growth, arrests cell cycle, and induces apoptosis. c-Met degrader-1 may overcome resistance to type Ib inhibitors[1].

Applications: Cancer-Kinase/protease

Formula: C45H53N7O3

References: [1]Min W, et al. Discovery of Potent and Selective c-Met Degraders for Hepatocellular Carcinoma Treatment. J Med Chem. 2024 Jul 4.

Molecular Weight: 739.95

Research Area: Cancer

Target: Apoptosis;c-Met/HGFR

• Artikelnummer: MEXHY-162679-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-162679-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK