Product Description: The cGAS protein is a nucleotidyl transferase that crucially mediates innate immunity by catalyzing the formation of 2',3'-cGAMP from ATP and GTP upon binding to double-stranded DNA (dsDNA). As a DNA sensor, cGAS detects exogenous and endogenous DNA, triggering STING1 activation and type I interferon production. cGAS Protein, Human (His) is the recombinant human-derived cGAS protein, expressed by E. coli , with C-6*His labeled tag. The total length of cGAS Protein, Human (His) is 522 a.a., with molecular weight of ~58.9 kDa.
Formula: 115004(Gene_ID)Q8N884-1 (M1-F522)(Accession)
Molecular Weight: Approximately 58.9 kDa
Compound Purity: 95.00