Product Description: Chlamydocin, a fungal metabolite, is a highly potent HDAC inhibitor, with an IC50 of 1.3 nM. Chlamydocin exhibits potent antiproliferative and anticancer activities. Chlamydocin induces apoptosis by activating caspase-3[1].
Applications: Cancer-programmed cell death
Formula: C28H38N4O6
References: [1]De Schepper S, et al. Inhibition of histone deacetylases by chlamydocin induces apoptosis and proteasome-mediated degradation of survivin. J Pharmacol Exp Ther. 2003;304(2):881-888.
CAS Number: 53342-16-8
Molecular Weight: 526.62
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Apoptosis;HDAC