Product Description: CRAMP (140-173) (mouse) TFA is a ortholog of human LL-37 antimicrobial peptide. CRAMP (140-173) (mouse) TFA inhibits LPS (HY-D1056)-induced responses, and can not colocalized with TLR3 in BEAS-2B cells[1].
Applications: COVID-19-immunoregulation
Formula: C178H302N50O46.xC2HF3O2
References: [1]Singh D, et al. The human antimicrobial peptide LL-37, but not the mouse ortholog, mCRAMP, can stimulate signaling by poly(I:C) through a FPRL1-dependent pathway. J Biol Chem. 2013;288(12):8258-8268.
Molecular Weight: 3878.61 (free acid)
Research Area: Infection
Target: Bacterial