Product Description: CXCL-CXCR1/2-IN-1 is an orally active ELR+CXCL-CXCR1/2 pathway inhibitor with an EC50 of 42.7 nM for CXCR2[1]. CXCL-CXCR1/2-IN-1 shows anticancer and antiangiogenic effects[1].
Applications: Cancer-Kinase/protease
Formula: C14H8Cl2N4O3S
References: [1]Oleksandr Grytsai, et al. A Potent Solution for Tumor Growth and Angiogenesis Suppression via an ELR+CXCL-CXCR1/2 Pathway Inhibitor. ACS Med. Chem. Lett. April 3, 2024.
CAS Number: 2415653-55-1
Molecular Weight: 383.21
Compound Purity: 99.64
Research Area: Cancer
Solubility: DMSO : 4.17 mg/mL (ultrasonic;warming;heat to 60°C)