CXCR4-IN-3

Product Description: CXCR4-IN-3 (compound XVI) is an orally active and potent inhibitor targeting the inflammation-related receptor CXCR4, with an IC50 of 3.2 nM. CXCR4-IN-3 exhibits potent antichemotactic activity, at 79.19±2.33% inhibition. CXCR4-IN-3 shows anti-inflammatory activity. CXCR4-IN-3 can be used for IBD (inflammatory bowel disease) research[1].

Applications: COVID-19-immunoregulation

Formula: C20H25N3O2

References: [1]Jiang X, et al. Synthetically Feasible De Novo Molecular Design of Leads Based on a Reinforcement Learning Model: AI-Assisted Discovery of an Anti-IBD Lead Targeting CXCR4. J Med Chem. 2024 Jun 27;67(12):10057-10075.

Molecular Weight: 339.43

Research Area: Inflammation/Immunology

Target: CXCR

• Artikelnummer: MEXHY-161735-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161735-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK