Cyclic L27-11, CAS 1221423-80-8

Product Description: Cyclic L27-11 is a cyclic peptide-like antibiotic with strong antibacterial activity against specific bacteria such as Pseudomonas sp. Cyclic L27-11 shows nanomolar antibacterial activity against Pseudomonas sp., especially Pseudomonas aeruginosa. Cyclic L27-11 interferes with the function of bacterial outer membrane protein LptD, preventing the normal transport of lipopolysaccharide (LPS), leading to the accumulation of membrane-like substances in bacterial cells, which in turn affects the survival of bacteria. Cyclic L27-11 can be used in the development of antibacterial agents[1].

Formula: C87H141N27O15

References: [1]Schmidt J, et al. Structural studies of β-hairpin peptidomimetic antibiotics that target LptD in Pseudomonas sp[J]. Bioorganic & medicinal chemistry, 2013, 21(18): 5806-5810.

CAS Number: 1221423-80-8

Molecular Weight: 1805.22

Research Area: Infection

Target: Bacterial

• Artikelnummer: MEXHY-P10548-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P10548-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK