Product Description: D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase. D-Ala-D-Ala is a bacterial endogenous metabolite[1][2].
References: [1]Kitamura Y, et al. Structure of D-alanine-D-alanine ligase from Thermus thermophilus HB8: cumulative conformational change and enzyme-ligand interactions. Acta Crystallogr D Biol Crystallogr. 2009 Oct;65(Pt 10):1098-106./[2]Tytgat I, et al. DD-ligases as a potential target for antibiotics: past, present and future. Curr Med Chem. 2009;16(20):2566-80.
CAS Number: 923-16-0
Molecular Weight: 160.17
Compound Purity: 97.0
Research Area: Others
Solubility: DMSO : 2 mg/mL (ultrasonic;adjust pH to 5 with HCl)/H2O : 100 mg/mL (ultrasonic)