EGFR-IN-118

Product Description: EGFR-IN-118 (Compound 4a) is an inhibitor for the tyrosine kinase EGFR. EGFR-IN-118 demonstrates anti-cancer property, inhibiting the proliferation of MCF-7 and PC3 with IC50 of 2.53 and 3.25 µg/ml. EGFR-IN-118 exhibits antioxidant efficacy, inhibiting the DPPH free radicals with IC50 of 10.04 µg/ml[1].

Applications: Cancer-Kinase/protease

Formula: C26H23N3O2S

References: [1]Seliem IA. DMF-DMA catalyzed Synthesis, molecular docking, in-vitro, in-silico design, and binding free energy studies of novel thiohydantoin derivatives as antioxidant and antiproliferative agents targeting EGFR tyrosine kinase and aromatase cytochrome P450 enzyme. Bioorg Chem. 2024 Sep;150:107601.

Molecular Weight: 441.54

Research Area: Cancer

Target: EGFR

• Artikelnummer: MEXHY-161866-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161866-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK