Product Description: FGFR2 degrader 1 (compound 28E) is a selectively degrader of FGFR2, with the DC50 of 0.645 nM. FGFR2 plays an important role in cancer research[1].
Formula: C40H39Cl2N9O6
References: [1]Zuli Hu, et al. Design, synthesis and antitumor activity of a novel FGFR2-selective degrader to overcome resistance of the FGFR2V564F gatekeeper mutation based on a pan-FGFR inhibitor. Eur J Med Chem. 2024 Sep 5:275:116612.