Product Description: The Frizzled-4/CD344 protein is a receptor for Wnt proteins and is associated with the classical β-catenin pathway, activating disheveled proteins, inhibiting GSK-3 kinase, and triggering Wnt target genes. In retinal vascularization, it acts as a receptor for Wnt proteins and Norrin (NDP), stimulating β-catenin accumulation and LEF/TCF-mediated transcription. Frizzled-4/CD344 Protein, Human (HEK293, Fc) is the recombinant human-derived Frizzled-4/CD344 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Frizzled-4/CD344 Protein, Human (HEK293, Fc) is 180 a.a., with molecular weight of ~43.3 kDa.
Formula: 8322(Gene_ID)Q9ULV1 (M1-E180)(Accession)
Molecular Weight: Approximately 43.3 kDa
Compound Purity: 96.0