Glucagon (1-29), bovine, human (hydrochloride), CAS 28270-04-4

Product Description: Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis[1]. Glucagon (1-29), bovine, human, porcine hydrochloride activates HNF4α and increases HNF4α phosphorylation[2][3].

Applications: Metabolism-sugar/lipid metabolism

Formula: C153H225N43O49S.ClH

References: [1]Song WJ, et al. Glucagon regulates hepatic kisspeptin to impair insulin secretion. Cell Metab. 2014 Apr 1;19(4):667-81./[2]Hirota K, et al. Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor. J Biol Chem. 2003 Apr 11;278(15):13056-60./[3]Song KH, et al. Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in humanhepatocytes: discordant regulation of bile acid synthesis and gluconeogenesis. Hepatology. 2006 Jan;43(1):117-25./[4]Capozzi ME, et al. Glucagon lowers glycemia when β-cells are active. JCI Insight. 2019 Jul 23;5. pii: 129954.

CAS Number: 28270-04-4

Molecular Weight: 3519.21

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: GCGR

• Artikelnummer: MEXHY-P0082A-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P0082A-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK