GPR110 peptide agonist P12, CAS 1778685-49-6

Product Description: GPR110 peptide agonist P12 is a peptide that acts as a GPR110 agonist. GPR110 peptide agonist P12 can significantly enhance the initial rate of GPR110 stimulated G protein GTPγS binding. GPR110 peptide agonist P12 mimics the action of natural ligands, causing the extracellular domain (ECD) of the GPR110 to dissociate from the seven transmembrane domains (7TM), exposing the β-strand-13/stalk region at the N-terminus of the 7TM domain, which acts as an agonist to activate G protein signaling. GPR110 peptide agonist P12 can be used in the study of developmental disorders and cancers related to GPR110[1].

Applications: Cancer-programmed cell death

Formula: C63H96N12O17S

References: [1]Stoveken H M, et al. Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist[J]. Proceedings of the National Academy of Sciences, 2015, 112(19): 6194-6199.

CAS Number: 1778685-49-6

Molecular Weight: 1325.57

Research Area: Cancer; Others

Target: Others

• Artikelnummer: MEXHY-P10495-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P10495-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK