GPR120 Agonist 5, CAS 1079821-35-4

Product Description: GPR120 Agonist 5 (compound 12) is an agonist targeting GPR120 (EC50=1.2 μM). GPR120 Agonist 5 promotes the release of glucagon-like 1 (GLP-1) by binding to the GPR120 receptor, which in turn binds to its receptors on pancreatic beta cells, increasing insulin secretion and thereby lowering blood sugar levels. GPR120 Agonist 5 also helps reduce chronic low-grade inflammation, which plays an important role in the pathogenesis of obesity, insulin resistance, and type 2 diabetes. GPR120 Agonist 5 can be used to investigate the mechanism of action of GPR120 in metabolic and inflammatory diseases[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C23H24N2O3

References: [1]Suzuki T, et al. Identification of G protein-coupled receptor 120-selective agonists derived from PPARγ agonists[J]. Journal of medicinal chemistry, 2008, 51(23): 7640-7644./[2]Shimpukade B, et al. Discovery of a potent and selective GPR120 agonist[J]. Journal of medicinal chemistry, 2012, 55(9): 4511-4515.

CAS Number: 1079821-35-4

Molecular Weight: 376.45

Research Area: Metabolic Disease; Inflammation/Immunology

Target: Free Fatty Acid Receptor

• Artikelnummer: MEXHY-109692-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-109692-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK