Granisetron, CAS 109889-09-0

Product Description: Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

Applications: Neuroscience-Neuromodulation

Formula: C18H24N4O

References: [1]Sanger GJ, Nelson DR. Selective and functional 5-hydroxytryptamine3 receptor antagonism by BRL 43694 (granisetron). Eur J Pharmacol. 1989 Jan 10;159(2):113-24./[2]Maleki-Dizaji N, Eteraf-Oskouei T, Fakhrjou A, The effects of 5HT3 receptor antagonist granisetron on inflammatory parameters and angiogenesis in the air-pouch model of inflammation. Int Immunopharmacol. 2010 Sep;10(9):1010-6./[3]Boccia RV, Gordan LN, Clark G, Efficacy and tolerability of transdermal granisetron for the control of chemotherapy-induced nausea and vomiting associated with moderately and highly emetogenic multi-day chemotherapy: a randomized, double-blind, phase III study. Support Care Cancer. 2011 Oct;19(10):1609-17.

CAS Number: 109889-09-0

Molecular Weight: 312.41

Compound Purity: 99.95

Research Area: Neurological Disease; Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

Target: 5-HT Receptor

• Artikelnummer: MEXHY-B0071-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0071-10.1
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK