HRS-4642, CAS 3033864-81-9

Product Description: HRS-4642 is a selective KRAS(G12D) inhibitor (Kd=0.083 nM) with anti-cancer activity. HRS-4642 synergizes with Carfilzomib (HY-10455) and exhibits significant in vivo potency to reshape the tumor microenvironment into an immune-activating microenvironment.

Applications: Cancer-Kinase/protease

Formula: C34H35F3N6O3

References: [1]Zhou C, et al. Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer. Cancer Cell. 2024 Jul 8;42(7):1286-1300.e8.

CAS Number: 3033864-81-9

Molecular Weight: 632.68

Research Area: Cancer

Target: Ras

• Artikelnummer: MEXHY-159127-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-159127-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK