JMV 449 (acetate), CAS 141863-45-8

Product Description: JMV 449 acetate is a potent neurotensin receptor agonist. JMV 449 acetate shows an IC50 of 0.15 nM for inhibition of 125I-neurotensin binding to neonatal mouse brain and an EC50 of 1.9 nM in contracting the guinea-pig ileum. JMV 449 acetate has highly potent and long-lasting hypothermic and analgesic effects in the mouse[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C40H70N8O9

References: [1]Lugrin D, et al. Reduced peptide bond pseudopeptide analogues of neurotensin: binding and biological activities, and in vitro metabolic stability. Eur J Pharmacol. 1991;205(2):191-198./[2]Dubuc I, et al. JMV 449: a pseudopeptide analogue of neurotensin-(8-13) with highly potent and long-lasting hypothermic and analgesic effects in the mouse. Eur J Pharmacol. 1992;219(2):327-329.

CAS Number: 141863-45-8

Molecular Weight: 807.03

Compound Purity: 99.91

Research Area: Neurological Disease

Solubility: H2O : 100 mg/mL (ultrasonic)

Target: Neurotensin Receptor

• Artikelnummer: MEXHY-P1256C-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P1256C-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK