Product Description: KGYY15 (Mouse KGYY15) is a CD40 targeting peptide, which weakly inhibits the CD40-CD40L interaction with IC50 of more than 1mM. KGYY15 activates 33% NF-κB pathway at 100 μM[1].
References: [1]Bojadzic D, et al., CD40-targeting KGYY15 peptides do not efficiently block the CD40-CD40L interaction. Diabetologia. 2019 Nov;62(11):2158-2160.