LDV-FITC (TFA)

Product Description: LDV-FITC TFA, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC TFA binds to the α4β1 integrin with high affinity (Kd: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn2+ respectively). LDV-FITC TFA can be used to detect α4β1 integrin affinity[1][2].

Applications: Cancer-programmed cell death

Formula: C69H81N11O17S.xC2HF3O2

References: [1]Hyduk SJ, et al. Phospholipase C, calcium, and calmodulin are critical for alpha4beta1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants. Blood. 2007 Jan 1;109(1):176-84./[2]Chigaev A, et al. Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation. J Biol Chem. 2001 Dec 28;276(52):48670-8.

Molecular Weight: 1368.51 (free base)

Research Area: Cancer

Target: Integrin

• Artikelnummer: MEXHY-P1188A-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P1188A-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK