MDC/CCL22, Mouse (His)

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Product Description: CCL22/MDC Protein,Mouse (His) is a CC chemokine that acts as a ligand for the CCR4 receptor and is a chemoattractant for CCR4-expressing cells such as Th2 cells, playing an important role in homeostatic and inflammatory responses. CCL22/MDC Protein, Mouse (His) is a recombinant mouse CCL22/MDC (G26-S92) protein expressed by E. coli with a his tag[1][2].

Formula: 20299(Gene_ID)O88430 (G26-S92)(Accession)

References: [1]Yano C, et al. Mechanism of Macrophage-Derived Chemokine/CCL22 Production by HaCaT Keratinocytes. Ann Dermatol. 2015 Apr;27(2):152-6./[2]Jan Korbecki, et al. CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of the Ligands of Receptors CCR1, CCR2, CCR3, and CCR4. Int J Mol Sci. 2020 Nov 9;21(21):8412./[3]Stefanie Scheu, et al. The C-C Chemokines CCL17 and CCL22 and Their Receptor CCR4 in CNS Autoimmunity. Int J Mol Sci. 2017 Nov 2;18(11):2306./[4]Vanessa Pinho, et al. The role of CCL22 (MDC) for the recruitment of eosinophils during allergic pleurisy in mice. J Leukoc Biol. 2003 Mar;73(3):356-62./[5]Jillian R Richter, et al. Macrophage-derived chemokine (CCL22) is a novel mediator of lung inflammation following hemorrhage and resuscitation. Shock. 2014 Dec;42(6):525-31.

Molecular Weight: Approximately 7.8 kDa

Compound Purity: 98.00

• Artikelnummer: MEXHY-P7248-100UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P7248-100UG
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK