Product Description: Melanin Concentrating Hormone, salmon is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2.
Applications: Metabolism-protein/nucleotide metabolism
Formula: C89H139N27O24S4
References: [1]An S, et al. Identification and characterization of a melanin-concentrating hormone receptor. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7576-81./[2]Della-Zuana O, et al. Acute and chronic administration of melanin-concentrating hormone enhances food intake and body weight in Wistar and Sprague-Dawley rats. Int J Obes Relat Metab Disord. 2002 Oct;26(10):1289-95./[3]Gomori A, et al. Chronic intracerebroventricular infusion of MCH causes obesity in mice. Melanin-concentrating hormone. Am J Physiol Endocrinol Metab. 2003 Mar;284(3):E583-8. Epub 2002 Nov 26.
CAS Number: 87218-84-6
Molecular Weight: 2099.48
Compound Purity: 98.40
Research Area: Metabolic Disease; Neurological Disease; Cardiovascular Disease; Endocrinology
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: MCHR1 (GPR24)