Product Description: Multi-Leu peptide (ML-peptide) is a potent inhibitor of PACE4 (Ki=22 nM). Multi-Leu peptide can competitively bind to the active site of PACE4 by simulating the substrate sequence of PACE4, thereby inhibiting its catalytic activity. Multi-Leu peptide can be used to study the specific mechanism of PACE4 in the development of prostate cancer[1].
Applications: Cancer-programmed cell death
Formula: C49H94N16O9
References: [1]Łepek T, et al. Macrocyclization of a potent PACE4 inhibitor: Benefits and limitations[J]. European journal of cell biology, 2017, 96(5): 476-485.
CAS Number: 1413058-07-7
Molecular Weight: 1051.37
Research Area: Cancer
Target: Others