(Nle20) H4 peptide (16−23), CAS 2042178-19-6

Product Description: [Nle20] H4 peptide (16−23) is a peptide with strong inhibitory activity against histone methyltransferase SETD8 (Kd=0.14 μM), which inhibits SETD8's methylation of histone H4 by competing with SETD8's substrate binding site. [Nle20] H4 peptide (16−23) can be used as a lead compound for anticancer therapy[1].

Formula: C47H88N20O9

References: [1]Judge R A, et al. Turning a substrate peptide into a potent inhibitor for the histone methyltransferase SETD8[J]. ACS Medicinal Chemistry Letters, 2016, 7(12): 1102-1106.

CAS Number: 2042178-19-6

Molecular Weight: 1077.33

Research Area: Cancer

Target: Histone Methyltransferase

• Artikelnummer: MEXHY-P10570-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P10570-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK