Product Description: PD 173955 analog 1 (Compound 26) is an analog of PD 173955 (HY-10395). PD 173955 analog 1 is an inhibitor for EGFR kinase, which exhibits antitumor and toxicological properties. PD 173955 analog 1 exhibits an in silico IC50 of 0.19 μM[1].
Applications: Cancer-Kinase/protease
Formula: C21H14Cl2N4O3
References: [1]Bagchi M C, et al., In silico evaluation of 6-(2, 6-dichlorophenyl)-pyrido [2, 3-d] pyrimidin-7 (8 H)-one compounds: an insight into design of less toxic anticancer drugs[J]. Medicinal Chemistry Research, 2016, 25: 123-134.
CAS Number: 185039-99-0
Molecular Weight: 441.27
Research Area: Cancer
Target: EGFR