Pip6a

Product Description: Pip6a is an arginine-rich cell-penetrating peptide. Pip6a has the ability to deliver associated cargoes across the plasma and endosomal membranes and is stable to serum proteolysis. Pip6a is composed of a hydrophobic core region flanked on each side by arginine-rich domains containing β-alanine and aminohexanoyl spacers. Pip6a-conjugated morpholino phosphorodiamidate oligomer (PMO) dramatically enhanced antisense oligonucleotide (ASO) delivery into striated muscles of myotonic dystrophy (DM1) mice[1].

Formula: C130H231N53O26

References: [1]Arnaud F Klein, et al. Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice. J Clin Invest. 2019 Nov 1;129(11):4739-4744.

Molecular Weight: 2952.56

Research Area: Others

Target: Others

• Artikelnummer: MEXHY-P10567-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P10567-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK