Pizuglanstat (hydrate), CAS 1584160-52-0

Product Description: Pizuglanstat hydrate (TAS-205) is a hematopoietic prostaglandin D synthase (HPGDS) inhibitor. TAS-205 selectively inhibits the synthesis of prostaglandin D2 (PGD2) in cell-based enzymatic tests and in vivo models, and effectively reduces the entry of eosinophils into the nasal cavity and late-stage nasal congestion. When used in combination with montelukast (HY-13315A), TAS-205 showed a significant synergistic inhibitory effect; when used in combination with fexofenadine (HY-B0801A), it also had a certain inhibitory effect on early and late nasal congestion.

Formula: C27H38N6O5

References: [1]Potential synergistic effects of novel hematopoietic prostaglandin D synthase inhibitor TAS-205 and different types of anti-allergic medicine on nasal obstruction in a Guinea pig model of experimental allergic rhinitis

CAS Number: 1584160-52-0

Molecular Weight: 526.63

Research Area: Inflammation/Immunology

Target: Prostaglandin Receptor

• Artikelnummer: MEXHY-109134A-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-109134A-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK