PPI-GIT1/β-Pix interaction-IN-1, CAS 2070916-70-8

Product Description: PPI-GIT1/β-Pix interaction-IN-1 is a potent and orally active GIT1/β-Pix protein-protein interaction (PPI) inhibitor with a KD value of 7.7 µM. PPI-GIT1/β-Pix interaction-IN-1 disrupts the GIT/PIX interaction can impact the activation of the downstream Rho GTPase Rac1 and Cdc42. PPI-GIT1/β-Pix interaction-IN-1 inhibits metastasis of gastric cancer[1].

Applications: Cancer-Kinase/protease

Formula: C23H21NO5

References: [1]Gu J, et, al. Construction of a synthetic methodology-based library and its application in identifying a GIT/PIX protein-protein interaction inhibitor. Nat Commun. 2022 Nov 23;13(1):7176./[2]Gu J, et, al. Construction of a synthetic methodology-based library and its application in identifying a GIT/PIX protein-protein interaction inhibitor. Nat Commun. 2022 Nov 23;13(1):7176.

CAS Number: 2070916-70-8

Molecular Weight: 391.42

Compound Purity: 98.94

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Ras

• Artikelnummer: MEXHY-152095-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-152095-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK