PROTAC ALK degrader-1

Product Description: PROTAC ALK degrader-1 (compound B1) is an ALK degrader based on PROTACs, with the DC50 of 26 nM in H3122 EML4-ALK. PROTAC ALK degrader-1 can be used to synthesis PROTAC ALK degrader-2 (HY-161750) with superior bioavailability[1].

Formula: C47H55ClN10O9S

References: [1]Shirui Wang, et al. Novel Amphiphilic PROTAC with Enhanced Pharmacokinetic Properties for ALK Protein Degradation. J Med Chem. 2024 Jun 27;67(12):9842-9856.

Molecular Weight: 971.52

Research Area: Cancer

Target: Anaplastic lymphoma kinase (ALK);PROTACs

• Artikelnummer: MEXHY-161749-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161749-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK